I didn't know that Nias had only given birth to her first offspring in 2010 - that goes towards explaining why it hadn't been identified earlier. Once Denver had experienced the issue, as others as mentioned this was able to assist the Adelaide keepers and unfortunately all of Karta's subsequent infants were stillborn.
The first clues were when Karta delivered her fourth offspring in 2011, which lived for four days. Keepers had named the infant ‘Sayang’ and tragically the post mortem revealed no milk in its stomach, indicating feeding had been unsuccessful.
Karta had been previously loaned to Perth to learn maternal care through observation, but ultimately any preparation was in vain when there was the overriding medical anomaly.